AUY-922 - CAS# 747412-49-3 size:2mg solid Kulkarni A

Kulkarni A

Daidzein-2c was used at 1 µM final concentration in various in vitro assays

Giranda VL

2017 Apr 3

phosphatidylinositol hydrolysis assays

AUY-922 - CAS# 747412-49-3 size:2mg solid Kulkarni AAUY 922, also known as Luminespib, NVP AUY922, VER52296, CAS No. 747412 49 3, is a derivative of 4, 5 diarylisoxazole and a third generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY 922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins; the inhibition of cell proliferation; and the elevation of heat shock